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Introduction

Knee cartilage replacement therapy is a treatment used to help people with damaged or worn cartilage in the knee. Cartilage is the smooth, rubbery tissue that covers the ends of bones where they meet in a joint. It helps bones slide easily and reduces pain during movement. When cartilage is worn away due to injury or arthritis, the bones can rub together, causing pain, stiffness, and trouble walking.

This therapy is not just one single operation; it includes a range of treatments that are designed to reduce pain, restore knee movement, and slow further damage. Since cartilage does not heal well on its own, doctors use these advanced methods to support long-term repair and help people return to daily activities with less pain.

Who May Need Knee Cartilage Replacement Therapy?

People who may benefit from knee cartilage replacement therapy include those who:

- Have chronic knee pain that affects daily life

- Have worn cartilage due to arthritis or injury

- Feel stiffness, swelling, or trouble bending the knee

- Have not improved after physical therapy or medicine

- Are young or active and want to avoid full knee replacement

- Want increased knee movement and less pain

- Find it hard to walk, climb stairs, or stand for long periods

A doctor must do a careful exam, including imaging tests like X-rays or MRI, to decide the best therapy.

Types of Knee Cartilage Replacement Therapy

There are several ways doctors treat cartilage damage. Common types of knee cartilage replacement therapy include:

1. Microfracture Surgery

This is a common surgical method. The surgeon makes tiny holes in the bone where cartilage is damaged. These small holes let cells from inside the bone come to the surface and form new cartilage-like tissue. It can help reduce pain and improve movement.

2. Autologous Cartilage Implantation

In this method, healthy cartilage cells are taken from the patient, grown in a lab, and then placed back into the knee where the damage is. These new cells help rebuild the cartilage surface.

3. Stem Cell Therapy

This biological treatment uses special cells called stem cells. They are taken from the patient’s body (like bone marrow or fat) and injected into the knee. The goal is to help the knee tissue repair itself and grow new cartilage. Some studies show this can reduce pain and improve knee function.

4. Knee Replacement Surgery (Partial or Total)

When cartilage damage is severe and other treatments have failed, knee replacement may be recommended. In this surgery, the damaged bone and cartilage are removed and replaced with artificial metal and plastic parts. It can be partial (only part of the knee) or total (the whole knee joint).

Each type has different benefits and is chosen based on the knee condition and patient’s needs.

Knee Cartilage Replacement Procedure

The knee cartilage replacement procedure varies by treatment type, but the basic steps are similar:

1. Medical Evaluation

A doctor checks your health, knee pain, and movement. Imaging tests help show how much cartilage is damaged.

2. Preparing for Therapy

For surgical treatments, fasting and stopping certain medicines may be required. For less invasive treatments, preparation may be minimal.

3. Procedure Day

○ Microfracture: Small cuts are made around the knee, and tiny holes are created in the bone to stimulate new cartilage growth.

○ Cartilage Implantation: Healthy cells are collected and later placed into the knee to help build cartilage.

○ Stem Cell Therapy: The doctor injects processed stem cells into the knee joint under image guidance.

○ Knee Replacement: The surgeon removes damaged cartilage and bone, then places artificial joint parts.

4. Immediate Care After

You may use crutches, braces, or protective devices. Pain medicines and antibiotics may be given to prevent infection.

5. Monitoring and Support

Regular follow-ups and imaging tests help the doctor see how the knee heals.

Different procedures take different amounts of time, but most cartilage repair therapies are done in a hospital or surgical centre under anaesthesia.

Recovery & Aftercare

Knee cartilage replacement recovery depends on the type of therapy:

- Rest and Protection: You may need crutches or a brace to protect the knee in the first weeks.

- Physical Therapy: Gentle exercises help rebuild strength and improve knee movement. This may continue for several months.

- Reducing Pain and Swelling: Ice, elevation, and prescribed medicines help reduce swelling and discomfort.

- Follow-Up Visits: Regular check-ups ensure healing is going well.

Recovery can take 3–6 months or longer, especially after surgical treatments. During recovery, it’s important to follow the doctor’s advice and avoid high-impact activities until the knee is strong and stable.

Risks & Possible Complications

Like any medical treatment, knee cartilage replacement therapy has some risks, which may include:

- Infection at the site of treatment or surgery

- Pain or swelling that lasts longer than expected

- Incomplete cartilage healing

- Blood clots or bleeding after surgery

- Need for additional surgery if repair does not work

- Stiffness or limited knee motion

Your doctor discusses these risks before the procedure and helps you decide if the benefits outweigh the risks.

Dr. Supriyo Saha

MS - Orthopaedics

OrthopedicsOrthopedics
Orthopedic SurgeonsOrthopedic Surgeons

Kinesis Knee Clinic, Hospital Rd, Goalafatak, Naihati, Kolkata, West Bengal, India, 743166

Dr. Jitendra Katariya (Physiotherapist)

Physiotherapist

PhysiotherapyPhysiotherapy

Achrol bus stand, NH 11C JAIPUR TO DELHI HIGHWAY Amber, Jaipur, Rajasthan, India, 303002

Dr. Aditya Sood

MBBS- MD- Sports Medicine

Sports MedicineSports Medicine

D33 ,Hauz Khas , Behind E block market, Near Bangla Pastry shop, Delhi, Delhi, India, 110016

Dr. Ayush Gupta

MBBS, MS - Orthopaedics ,Dip FM , FASM , SCOT

OrthopedicsOrthopedics

1026/40 DDA flats, main road, Guru Ravidas Marg, near fish market, Kalkaji, Delhi, Delhi, India, 110019

Dr. Sridhar Maryada Reddy

MBBS- MS-Orthopedics

OrthopedicsOrthopedics

Navjeevan tower, Navjeevan Advanced Diagnostic Laboratories and Health Care Centre, Near Saket Square,, Old Palasia, Indore, Madhya Pradesh 452001, Indore, Madhya Pradesh, India, 452011

Dr. Abhishek Kalantri

Knee & Shoulder Ligament specialist Arthroscopy Surgeon

Orthopedic SurgeonsOrthopedic Surgeons
Sports MedicineSports Medicine
Hand SurgeonHand Surgeon

21/1 LIG Square opposite DNS Hospital, AB road Indore, Indore, Madhya Pradesh, India, 452010

Dr. Ashish Gupta

DNB/MS orthopaedics

Orthopedic SurgeonsOrthopedic Surgeons
OrthopedicsOrthopedics

A-2348 ground floor Greenfield faridabad, Faridabad, Haryana, India, 121003

Frequently Asked Questions

It is a treatment to repair or replace damaged cartilage in the knee to reduce pain and improve movement. Methods include surgery, cartilage implants, and stem cell therapy.

People with knee pain from worn cartilage that does not improve with medicine or physical therapy may be candidates. A doctor must evaluate each case.

Recovery varies by treatment. Most patients need physical therapy for several months and must avoid heavy activities at first.

Most procedures are safe when done by experienced doctors. There are risks like infection or pain, but careful preparation and aftercare reduce complications.

Cartilage has limited ability to heal on its own. Replacement therapies aim to help new tissue form, but results vary by person and method.

Some people may still need a partial or total knee replacement if cartilage replacement therapy does not provide enough relief.

Stem cell therapy may help some people by supporting cartilage repair, but success can vary and is still being studied.